Abstract Excess production of reactive oxygen species (ROS) caused by hyperglycemia is a major risk factor for heart failure.We previously reported that transient receptor potential canonical 3 (TRPC3) channel mediates pressure overload-induced maladaptive cardiac fibrosis by forming stably functional complex with NADPH oxidase 2 (Nox2).Although TR
Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris
Abstract Background Pichia pastoris is widely used as a production platform for heterologous proteins and model organism for organelle proliferation.Without a published genome sequence available, strain and process development relied mainly on analogies to other, well studied yeasts like Saccharomyces cerevisiae.Results To investigate specific feat
Quantitative or Qualitative: Selecting the Right Methodological Approach for Credible Evidence
This article provides insight into how an adequate approach to selecting methods can establish credible and actionable evidence.The authors offer Clothing - Junior Bottoms - Pants strategies to effectively support Extension professionals, including program developers and evaluators, in being more deliberate when selecting appropriate qualitative an
The stomatogastric nervous system as a model for studying sensorimotor interactions in real-time closed-loop conditions
The perception of proprioceptive signals that report the internal state of the Tie Back body is one of the essential tasks of the nervous system and helps to continuously adapt body movements to changing circumstances.Despite the impact of proprioceptive feedback on motor activity it has rarely been studied in conditions in which motor output and s